https://pinboard.in/u:jm/public/ recent bookmarks from jm 2021-12-15T12:03:12+00:00 https://www.kqed.org/news/11898991/it-saved-my-life-depression-treatment-turns-lives-around-in-five-days jmA recent randomized control trial, published in The American Journal of Psychiatry, shows astounding results are possible in five days or less. Almost 80% of patients crossed into remission — meaning they were symptom-free within days. This is compared to about 13% of people who received the placebo treatment. Patients did not report any serious side effects. The most common complaint was a light headache. [...] “This study not only showed some of the best remission rates we've ever seen in depression,” said Shan Siddiqi, a Harvard psychiatrist not connected to the study, “but also managed to do that in people who had already failed multiple other treatments.” Siddiqi also said the study’s small sample size, which is only 29 patients, is not cause for concern. “Often, a clinical trial will be terminated early [according to pre-specified criteria] because the treatment is so effective that it would be unethical to continue giving people placebo,” said Siddiqi. “That's what happened here. They'd originally planned to recruit a much larger sample, but the interim analysis was definitive.” ]]> depression fmri health neuroscience medicine rtms brain rcts https://pinboard.in/ https://pinboard.in/u:jm/b:0a321106fe1d/ 2021-10-14T16:04:52+00:00 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304992/ jmWe found that the fruit fly olfactory circuit evolved a variant of a Bloom filter to assess the novelty of odors. Compared with a traditional Bloom filter, the fly adjusts novelty responses based on two additional features: the similarity of an odor to previously experienced odors and the time elapsed since the odor was last experienced. We elaborate and validate a framework to predict novelty responses of fruit flies to given pairs of odors. We also translate insights from the fly circuit to develop a class of distance- and time-sensitive Bloom filters that outperform prior filters when evaluated on several biological and computational datasets. Overall, our work illuminates the algorithmic basis of an important neurobiological problem and offers strategies for novelty detection in computational systems. ]]> fruit-flies data-structures algorithms brains neuroscience smell https://pinboard.in/ https://pinboard.in/u:jm/b:daae14ef0275/ 2018-07-02T09:49:24+00:00 https://www.media.mit.edu/projects/sleep-creativity/overview/ jmUsing Dormio you fall asleep as you normally would, but the transition into stage 2 sleep is tracked and interrupted. This suspends you in a semi-lucid state where microdreams are inceptable, allowing direction of your dreams.  ]]> dreaming dreams science neuroscience brain sleep lucid-dreaming via:fp dormio https://pinboard.in/ https://pinboard.in/u:jm/b:adade499b3c9/ 2016-06-03T15:24:53+00:00 http://biorxiv.org/content/biorxiv/early/2016/05/26/055624.full.pdf jm via:bos neuroscience microprocessors 6502 computers hardware wetware brain biology neural-systems https://pinboard.in/ https://pinboard.in/u:jm/b:adbeaa302730/ 2015-03-20T13:47:06+00:00 http://www.nature.com/news/the-myopia-boom-1.17120?WT.mc_id=TWT_NatureNews jm eyes health neuroscience science vision nature myopia short-sightedness https://pinboard.in/ https://pinboard.in/u:jm/b:6ae377b135b6/ 2013-01-15T10:40:01+00:00 http://neurocritic.blogspot.co.uk/2013/01/fisher-price-synesthesia.html jm fisher-price synesthesia synaesthesia colors colours sight neuroscience brain via-dave-green toys https://pinboard.in/ https://pinboard.in/u:jm/b:ace087dbfbf1/ 2011-11-02T22:00:44+00:00 http://www.orionmagazine.org/index.php/articles/article/6474/ jm octopus animals biology consciousness neuroscience science https://pinboard.in/ https://pinboard.in/u:jm/b:05f9053e995b/ 2011-04-19T21:05:17+00:00 http://www.nytimes.com/2011/04/17/magazine/mag-17Sleep-t.html?_r=3 jm sleep rest brain science neuroscience https://pinboard.in/ https://pinboard.in/u:jm/b:41f55953a498/