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    <title>Antidepressants and health-related quality of life (HRQoL) for patients with depression: Analysis of the medical expenditure panel survey from the United States</title>
    <dc:date>2022-04-28T02:28:47+00:00</dc:date>
    <link>https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0265928</link>
    <dc:creator>Michael.Massing</dc:creator><description><![CDATA[Despite the empirical literature demonstrating the efficacy of antidepressant medications for treatment of depression disorder, these medications’ effect on patients’ overall well-being and health-related quality of life (HRQoL) remains controversial.... 

The real-world effect of using antidepressant medications does not continue to improve patients’ HRQoL over time. ]]></description>
<dc:subject>depression research peer-reviewed human cohort retrospective in vivo situ antidepressants QoL HRQoL quality of life health-related long-term longitudinal benefit</dc:subject>
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<item rdf:about="https://www.endocrinologyadvisor.com/home/topics/thyroid/hyperparathyroidism-osteocalcin-cortisol-levels-affect-depression-anxiety/?hmSubId=YY-zPItNrOw1&amp;hmEmail=Jw_YJjhVyI84iX-Oepu7iw7YiNSIB0EK31LP7LVx8w01&amp;NID=-1&amp;email_hash=983917dd1eba78eb44e393fea65df5ca&amp;mpweb=1323-153535-7624403">
    <title>Depression, Anxiety Associated with Osteocalcin, Cortisol in Hyperparathyroidism - Endocrinology Advisor</title>
    <dc:date>2021-09-20T01:43:46+00:00</dc:date>
    <link>https://www.endocrinologyadvisor.com/home/topics/thyroid/hyperparathyroidism-osteocalcin-cortisol-levels-affect-depression-anxiety/?hmSubId=YY-zPItNrOw1&amp;hmEmail=Jw_YJjhVyI84iX-Oepu7iw7YiNSIB0EK31LP7LVx8w01&amp;NID=-1&amp;email_hash=983917dd1eba78eb44e393fea65df5ca&amp;mpweb=1323-153535-7624403</link>
    <dc:creator>Michael.Massing</dc:creator><description><![CDATA[Results of a bivariate model indicated that cortisol concentration at 8:00 [a.m.] was “significantly and negatively correlated” with social function. Serum osteocalcin concentration was also significantly and negatively correlated with BDI, while serum PTH and calcium were not correlated with any questionnaire scores. After controlling for age, sex, and disease duration, the cortisol correlation remained true.

Further adjustments for PTH, vitamin D, phosphorus, and calcium showed a continued significant and negative correlation with cortisol at 8:00 and social function score.]]></description>
<dc:subject>cortison depression anxiety correlation peer-reviewed research endocrine in vivo clinical study human trial</dc:subject>
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    <title>PRIME® Online CE - Patient-Provider Collaborative Decisions in Management of Major Depressive Disorder</title>
    <dc:date>2019-06-02T16:47:01+00:00</dc:date>
    <link>https://primeinc.org/cme/online/1548/Patient-Provider_Collaborative_Decisions_in_Management_of_Major_Depressive_Disorder?s=eh&amp;data=U2FsdGVkX1%2F7fX6LVpuXZ5TVdwoYCV+IcDAjz2Dqllg%3D&amp;xid=nl_mpt_DHE_2019-05-13</link>
    <dc:creator>Michael.Massing</dc:creator><dc:subject>depression major treatment management care self</dc:subject>
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    <title>Why did Ted Cruz change his name? - Quora</title>
    <dc:date>2019-02-14T01:33:46+00:00</dc:date>
    <link>https://www.quora.com/Why-did-Ted-Cruz-change-his-name</link>
    <dc:creator>Michael.Massing</dc:creator><dc:subject>Ted Cruz name change anti-Batista resistance father mother depression biography</dc:subject>
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<item rdf:about="http://journals.sagepub.com/doi/full/10.1177/0269216318793286">
    <title>Psychological morbidity and general health among family caregivers during end-of-life cancer care: A retrospective census survey - Gunn Grande, Christine Rowland, Bernard van den Berg, Barbara Hanratty, 2018</title>
    <dc:date>2018-09-02T02:40:00+00:00</dc:date>
    <link>http://journals.sagepub.com/doi/full/10.1177/0269216318793286</link>
    <dc:creator>Michael.Massing</dc:creator><description><![CDATA[Design:
National 4-month post-bereavement postal census survey of family carers of people who died from cancer, retrospectively measuring carers’ psychological health (General Health Questionnaire-12) and general health (EuroQoL EQ-Visual Analogue Scale) during the patient’s last 3 months of life.

Participants:
N = 1504 (28.5%) of all 5271 people who registered the death of a relative from cancer in England during 2 weeks in 2015 compared with data from the Health Survey for England 2014 (N = 6477–6790).

Results:
Psychological morbidity at clinically significant levels (General Health Questionnaire-12 ⩾4) was substantially higher among carers than the general population (83% vs 15%), with prevalence five to seven times higher across all age groups. Overall, carers’ general health scores were lower than population scores, median 75 (interquartile range, 50–80) versus 80 (interquartile range, 70–90), but differences were more marked at younger ages. Female carers had worse psychological morbidity and general health than male carers.

Conclusion:
Levels of psychological morbidity among family carers during end-of-life caregiving are far higher than indicated by previous research, indicating a substantial public health problem. Consistent assessment and support for carers to prevent breakdown in caregiving may produce cost savings in long term.]]></description>
<dc:subject>caring caregiving end-of-life terminal cancer patients family members depression correlation anxiety stress toll peer-reviewed research human in vivo situ general health</dc:subject>
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<item rdf:about="https://www.sciencedaily.com/releases/2018/08/180821112010.htm">
    <title>Largest brain study of 62,454 scans identifies drivers of brain aging: Schizophrenia, cannabis use, and alcohol abuse are just several disorders that are related to accelerated brain aging -- ScienceDaily</title>
    <dc:date>2018-09-02T02:25:33+00:00</dc:date>
    <link>https://www.sciencedaily.com/releases/2018/08/180821112010.htm</link>
    <dc:creator>Michael.Massing</dc:creator><description><![CDATA[Researchers studied 128 brain regions to predict the chronological age of the patient. Older age predicted from the scan compared to the actual chronological age was interpreted as accelerated aging. The study found that a number of brain disorders and behaviors predicted accelerated aging, especially schizophrenia, which showed an average of 4 years of premature aging, cannabis abuse (2.8 years of accelerated aging), bipolar disorder (1.6 years accelerated aging), ADHD (1.4 years accelerated aging) and alcohol abuse (0.6 years accelerated aging). Interestingly, the researchers did not observe accelerated aging in depression and aging, which they hypothesize may be due to different types of brain patterns for these disorders.]]></description>
<dc:subject>brain aging rate accelerated imaging in vivo human correlation peer-reviewed research population depression</dc:subject>
<dc:source>https://pinboard.in/</dc:source>
<dc:identifier>https://pinboard.in/u:Michael.Massing/b:47ea5a5322b1/</dc:identifier>
<taxo:topics><rdf:Bag>	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:brain"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:aging"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:rate"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:accelerated"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:imaging"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:in"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:vivo"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:human"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:correlation"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:peer-reviewed"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:research"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:population"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:depression"/>
</rdf:Bag></taxo:topics>
</item>
<item rdf:about="https://www.sciencedirect.com/science/article/pii/S2213177918302269?via%3Dihub">
    <title>Long-Chain Omega-3 Fatty Acid Supplements in Depressed Heart Failure Patients: Results of the OCEAN Trial - ScienceDirect</title>
    <dc:date>2018-09-02T02:19:49+00:00</dc:date>
    <link>https://www.sciencedirect.com/science/article/pii/S2213177918302269?via%3Dihub</link>
    <dc:creator>Michael.Massing</dc:creator><description><![CDATA[Patients with CHF and depression had low blood omega-3 concentrations that were associated with an elevated risk of mortality.

Methods

This study was a randomized, double-blind, placebo-controlled pilot clinical trial using a 400/200 eicosapentaenoic acid (EPA)/docosahexaenoic acid (DHA) fish oil at 2 g and an almost pure EPA at 2 g, compared with a matched placebo, daily for 12 weeks for patients with CHF and major depressive disorder. Statistical analyses included the intention-to-treat population and “completers” (defined as participants consuming ≥70% of the capsules and completing the final endpoint evaluation between 10 and 14 weeks).

Results

A total of 108 patients with CHF and major depressive disorder and a score ≥18 on the Hamilton Depression Scale who were randomized at 1:1:1 to the 3 interventions at 3 enrolling centers from June 12, 2014, to May 19, 2016; 80 (74.1%) qualified as completers. Intention-to-treat analyses revealed that the levels of all omega-3 variables were significantly elevated in the omega-3 groups, whereas the placebo group showed little change; there were no between-group differences with overall depression measurements. Per-protocol exploratory analyses showed that scores on the social functioning measurement of the 36-item Short Form Health Survey improved notably in the 400/200 EPA/DHA (p = 0.040) and EPA (p = 0.10) groups compared with the placebo group. Spearman correlation analysis indicated that increased omega-3 indices were associated with improved cognitive depressive symptoms.

Conclusions

Omega-3 supplementation resulted in significant increases in omega-3 levels in red blood cell counts, corresponding to a particular compound of omega-3. Changes in cognitive depressive symptoms and social function were in favor of the omega-3 supplementation. Further studies with larger sample sizes are necessary to confirm the benefits of omega-3 supplementation on modifying psychosocial factors for patients with CHF. (Omega-3 Supplementation for Co-Morbid Depression and Heart Failure Treatment [OCEAN]; NCT02057406)]]></description>
<dc:subject>depression CHF major depressive disorder peer-reviewed research human clinical trial in vivo situ cognition functional improvement treatment cognitive comorbidity mortality risk benefit supplements omega-3 DHA EPA RCT</dc:subject>
<dc:source>https://pinboard.in/</dc:source>
<dc:identifier>https://pinboard.in/u:Michael.Massing/b:db9901efb89e/</dc:identifier>
<taxo:topics><rdf:Bag>	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:depression"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:CHF"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:major"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:depressive"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:disorder"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:peer-reviewed"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:research"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:human"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:clinical"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:trial"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:in"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:vivo"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:situ"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:cognition"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:functional"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:improvement"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:treatment"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:cognitive"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:comorbidity"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:mortality"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:risk"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:benefit"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:supplements"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:omega-3"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:DHA"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:EPA"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:RCT"/>
</rdf:Bag></taxo:topics>
</item>
<item rdf:about="https://www.aarp.org/health/conditions-treatments/info-2018/volunteering-staves-off-dementia.html?cmp=EMC-DSO-NLC-WBLTR---MCTRL-080318-F4-3122652&amp;ET_CID=3122652&amp;ET_RID=34232012&amp;mi_u=34232012&amp;mi_ecmp=20180803_WEBLETTER_Member_Control_Winner_339600_468007&amp;encparam=mf7l0H93t2B106%2bzkIEr28eoKdSx77R5bpRppboXUI8%3d">
    <title>Can Volunteering Fight Dementia?</title>
    <dc:date>2018-09-02T01:28:39+00:00</dc:date>
    <link>https://www.aarp.org/health/conditions-treatments/info-2018/volunteering-staves-off-dementia.html?cmp=EMC-DSO-NLC-WBLTR---MCTRL-080318-F4-3122652&amp;ET_CID=3122652&amp;ET_RID=34232012&amp;mi_u=34232012&amp;mi_ecmp=20180803_WEBLETTER_Member_Control_Winner_339600_468007&amp;encparam=mf7l0H93t2B106%2bzkIEr28eoKdSx77R5bpRppboXUI8%3d</link>
    <dc:creator>Michael.Massing</dc:creator><description><![CDATA[For twelve years, Gupta studied more than 64,000 subjects 60 and older who participated in the University of Michigan Health and Retirement Study and discovered that those who did volunteer work for 100 hours a year — a mere two hours a week — scored about 6 percent higher in cognitive testing than non-volunteers did. She made sure to control for other factors that affect cognition — depression and changes in the volunteer’s own health — and the results were statistically significant.

Gupta’s study adds to burgeoning evidence that lifestyle changes can help prevent, or seriously delay, dementia and that along with things like diet and exercise, volunteering may be a notable weapon in the fight.

A study released last year by the University of Calgary showed that volunteering one hour a week made 1,0001 Swedish retirees 2.44 less likely to develop dementia. The study's author, Yannick Griep, who followed his subjects for five years after their retirement, cautioned that sporadic volunteering provided no advantage over not volunteering at all. The non-paid work, he stressed, had to be regular for the brain-preserving benefit to accrue. What's more, not all volunteer efforts may be equally effective. “The activity has to benefit others who are not your core family,” said Griep, “for example, helping out a church, a school, a library, a homeless shelter or some sort of charity organization.”

Yet another study, by the Corporation for National and Community Service, whose Senior Companion program involves seniors volunteering 15 to 40 hours a week, revealed that 40 percent of those who rated their health as “fair” or “poor” at the onset rated it as “good” after one year of volunteering. Depression is a major factor in dementia, and 70 percent of those reporting five or more depression symptoms at the beginning of volunteering reported fewer symptoms after their year as volunteers.

]]></description>
<dc:subject>depression dementia comorbidity correlation per-reviewed research activity altruism volunteering behavioral self care</dc:subject>
<dc:source>https://pinboard.in/</dc:source>
<dc:identifier>https://pinboard.in/u:Michael.Massing/b:8ea924659a82/</dc:identifier>
<taxo:topics><rdf:Bag>	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:depression"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:dementia"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:comorbidity"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:correlation"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:per-reviewed"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:research"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:activity"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:altruism"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:volunteering"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:behavioral"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:self"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:care"/>
</rdf:Bag></taxo:topics>
</item>
<item rdf:about="https://twitter.com/i/web/status/972885907706667010">
    <title>Twitter</title>
    <dc:date>2018-03-11T17:24:10+00:00</dc:date>
    <link>https://twitter.com/i/web/status/972885907706667010</link>
    <dc:creator>Michael.Massing</dc:creator><description><![CDATA[Belated realization: The trade-off for the apparent spontaneous remission of the #depression is that the #anxiety d… ]]></description>
<dc:subject>anxiety depression</dc:subject>
<dc:source>https://twitter.com/</dc:source>
<dc:identifier>https://pinboard.in/u:Michael.Massing/b:55b4d92c30f8/</dc:identifier>
<taxo:topics><rdf:Bag>	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:anxiety"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:depression"/>
</rdf:Bag></taxo:topics>
</item>
<item rdf:about="http://johnpavlovitz.com/2017/07/21/please-stop-calling-suicide-selfish/">
    <title>Please Stop Calling Suicide Victims &quot;Selfish&quot; or &quot;Weak&quot;</title>
    <dc:date>2017-07-22T15:58:41+00:00</dc:date>
    <link>http://johnpavlovitz.com/2017/07/21/please-stop-calling-suicide-selfish/</link>
    <dc:creator>Michael.Massing</dc:creator><description><![CDATA[But we should never use the moment to insult the dead by trying to shame them after they’re gone. Believe me, they really wanted to stay.

They did the very best they could in the worst seconds of their lives. They were as brave and strong and selfless as they were able to be in that moment.

There but for the grace of God go the critics.

May you always be such strangers to the dark.]]></description>
<dc:subject>suicide depression despair ghoulishness</dc:subject>
<dc:source>https://pinboard.in/</dc:source>
<dc:identifier>https://pinboard.in/u:Michael.Massing/b:ca28f7c67b25/</dc:identifier>
<taxo:topics><rdf:Bag>	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:suicide"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:depression"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:despair"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:ghoulishness"/>
</rdf:Bag></taxo:topics>
</item>
<item rdf:about="http://www.sciencealert.com/scientists-can-do-a-brain-scan-to-tell-if-you-re-depressed-and-what-treatment-is-needed">
    <title>There's now a brain scan to tell if you're depressed – and what treatment is needed - ScienceAlert</title>
    <dc:date>2017-04-21T23:49:39+00:00</dc:date>
    <link>http://www.sciencealert.com/scientists-can-do-a-brain-scan-to-tell-if-you-re-depressed-and-what-treatment-is-needed</link>
    <dc:creator>Michael.Massing</dc:creator><dc:subject>machine learning patterns correlation research brain in vivo human clinical MRI scan depression limbic system regions treatment indication responsiveness</dc:subject>
<dc:source>https://pinboard.in/</dc:source>
<dc:identifier>https://pinboard.in/u:Michael.Massing/b:4f1e385b51c2/</dc:identifier>
<taxo:topics><rdf:Bag>	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:machine"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:learning"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:patterns"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:correlation"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:research"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:brain"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:in"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:vivo"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:human"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:clinical"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:MRI"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:scan"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:depression"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:limbic"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:system"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:regions"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:treatment"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:indication"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:responsiveness"/>
</rdf:Bag></taxo:topics>
</item>
<item rdf:about="https://hideandsink.wordpress.com/2016/04/17/rosalind-robertson-21-tips-to-keep-your-shit-together-when-youre-depressed/">
    <title>ROSALIND ROBERTSON: 21 Tips to Keep Your Shit Together When You’re Depressed – hide and sink</title>
    <dc:date>2017-04-15T19:03:06+00:00</dc:date>
    <link>https://hideandsink.wordpress.com/2016/04/17/rosalind-robertson-21-tips-to-keep-your-shit-together-when-youre-depressed/</link>
    <dc:creator>Michael.Massing</dc:creator><dc:subject>depression self treatment amelioration behavior behavioral</dc:subject>
<dc:source>https://pinboard.in/</dc:source>
<dc:identifier>https://pinboard.in/u:Michael.Massing/b:c4020b442684/</dc:identifier>
<taxo:topics><rdf:Bag>	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:depression"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:self"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:treatment"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:amelioration"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:behavior"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:behavioral"/>
</rdf:Bag></taxo:topics>
</item>
<item rdf:about="https://www.ncbi.nlm.nih.gov/pubmed/16184071">
    <title>A double-blind, placebo-controlled, exploratory trial of chromium picolinate in atypical depression: effect on carbohydrate craving. - PubMed - NCBI</title>
    <dc:date>2017-03-13T18:50:08+00:00</dc:date>
    <link>https://www.ncbi.nlm.nih.gov/pubmed/16184071</link>
    <dc:creator>Michael.Massing</dc:creator><description><![CDATA[In a small pilot trial, patients with atypical depression demonstrated significant positive therapeutic response to chromium picolinate. This finding is of interest because of the demonstrated link between depression, decreased insulin sensitivity, and subsequent diabetes and chromium picolinate's insulin enhancing effect.
METHODS:
: In this double-blind, multicenter, 8-week replication study, 113 adult outpatients with atypical depression were randomized 2:1 to receive 600 mug/day of elemental chromium, as provided by chromium picolinate (CrPic), or placebo. Primary efficacy measures were the 29-item Hamilton Depression Rating Scale (HAM-D-29) and the Clinical Global Impressions Improvement Scale (CGI-I).
RESULTS:
: Of the 113 randomized patients, 110 (70 CrPic, 40 placebo) constituted the intent-to-treat (ITT) population (i.e., received at least one dose of study medication and completed at least one efficacy evaluation) and 75 (50 CrPic, 25 placebo) were evaluable (i.e., took at least 80% of study drug with no significant protocol deviations). In the evaluable population, mean age was 46 years, 69% were female, 81% were Caucasian, and mean body mass index (BMI) was 29.7. There was no significant difference between the CrPic and placebo groups in both the ITT and evaluable populations on the primary efficacy measures, with both groups showing significant improvement from baseline on total HAM-D-29 scores during the course of treatment (p < 0.0001). However, in the evaluable population, the CrPic group showed significant improvements from baseline compared with the placebo group on 4 HAM-D-29 items: appetite increase, increased eating, carbohydrate craving, and diurnal variation of feelings. A supplemental analysis of data from the subset of 41 patients in the ITT population with high carbohydrate craving (26 CrPic, 15 placebo; mean BMI = 31.1) showed that the CrPic patients had significantly greater response on total HAM-D-29 scores than the placebo group (65% vs. 33%; p < 0.05) as well as significantly greater improvements on the following HAM-D-29 items: appetite increase, increased eating, carbohydrate craving, and genital symptoms (e.g., level of libido). Chromium treatment was well-tolerated.
LIMITATIONS:
: The study did not include a placebo run-in period, did not require minimum duration or severity of depression, and enrolled patients with major depression, dysthymia, or depression NOS.
CONCLUSIONS:
: In a population of adults with atypical depression, most of whom were overweight or obese, CrPic produced improvement on the following HAM-D-29 items: appetite increase, increased eating, carbohydrate craving, and diurnal variation of feelings. In a subpopulation of patients with high carbohydrate craving, overall HAM-D-29 scores improved significantly in patients treated with CrPic compared with placebo. The results of this study suggest that the main effect of chromium was on carbohydrate craving and appetite regulation in depressed patients and that 600 mug of elemental chromium may be beneficial for patients with atypical depression who also have severe carbohydrate craving. Further studies are needed to evaluate chromium in depressed patients specifically selected for symptoms of increased appetite and carbohydrate craving as well as to determine whether a higher dose of chromium would have an effect on mood.]]></description>
<dc:subject>carbohydrate craving chromium picolinate peer-reviewed research depression psychotropic effects .Plexus .week2</dc:subject>
<dc:source>https://pinboard.in/</dc:source>
<dc:identifier>https://pinboard.in/u:Michael.Massing/b:2ec1db848653/</dc:identifier>
<taxo:topics><rdf:Bag>	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:carbohydrate"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:craving"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:chromium"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:picolinate"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:peer-reviewed"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:research"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:depression"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:psychotropic"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:effects"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:.Plexus"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:.week2"/>
</rdf:Bag></taxo:topics>
</item>
<item rdf:about="https://www.ncbi.nlm.nih.gov/pubmed/25838140">
    <title>Dietary chromium supplementation for targeted treatment of diabetes patients with comorbid depression and binge eating. - PubMed - NCBI</title>
    <dc:date>2017-03-13T17:59:08+00:00</dc:date>
    <link>https://www.ncbi.nlm.nih.gov/pubmed/25838140</link>
    <dc:creator>Michael.Massing</dc:creator><description><![CDATA[Dietary chromium supplementation for the treatment of diabetes remains controversial. The prevailing view that chromium supplementation for glucose regulation is unjustified has been based upon prior studies showing mixed, modest-sized effects in patients with type 2 diabetes (T2DM). Based on chromium's potential to improve insulin, dopamine, and serotonin function, we hypothesize that chromium has a greater glucoregulatory effect in individuals who have concurrent disturbances in dopamine and serotonin function--that is, complex patients with comorbid diabetes, depression, and binge eating. We propose, as suggested by the collective data to date, the need to go beyond the "one size fits all" approach to chromium supplementation and put forth a series of experiments designed to link physiological and neurobehavioral processes in the chromium response phenotype.]]></description>
<dc:subject>chromium picolinate comorbidity depression T2D type 2 diabetes individual response variability treatment intervention psychotropic appetite carbohydrate craving peer-reviewed research Plexus opinion overview .Plexus .week2</dc:subject>
<dc:source>https://pinboard.in/</dc:source>
<dc:identifier>https://pinboard.in/u:Michael.Massing/b:7a30499f7942/</dc:identifier>
<taxo:topics><rdf:Bag>	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:chromium"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:picolinate"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:comorbidity"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:depression"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:T2D"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:type"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:2"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:diabetes"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:individual"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:response"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:variability"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:treatment"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:intervention"/>
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	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:carbohydrate"/>
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</item>
<item rdf:about="https://www.ncbi.nlm.nih.gov/pubmed/25037773">
    <title>Possible involvement of corticosterone and serotonin in antidepressant and antianxiety effects of chromium picolinate in chronic unpredictable mild... - PubMed - NCBI</title>
    <dc:date>2017-03-13T17:40:48+00:00</dc:date>
    <link>https://www.ncbi.nlm.nih.gov/pubmed/25037773</link>
    <dc:creator>Michael.Massing</dc:creator><dc:subject>in vivo animal depression stress chromium picolinate .Plexus peer-reviewed research psychotropic anxiety corticosterone .week2</dc:subject>
<dc:source>https://pinboard.in/</dc:source>
<dc:identifier>https://pinboard.in/u:Michael.Massing/b:9e5f579897ab/</dc:identifier>
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	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:corticosterone"/>
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</item>
<item rdf:about="https://www.ncbi.nlm.nih.gov/pubmed/26180581">
    <title>Psychiatric Disorders and Polyphenols: Can They Be Helpful in Therapy? - PubMed - NCBI</title>
    <dc:date>2017-03-13T17:22:35+00:00</dc:date>
    <link>https://www.ncbi.nlm.nih.gov/pubmed/26180581</link>
    <dc:creator>Michael.Massing</dc:creator><description><![CDATA[The prevalence of psychiatric disorders permanently increases. Polyphenolic compounds can be involved in modulation of mental health including brain plasticity, behaviour, mood, depression, and cognition. In addition to their antioxidant ability other biomodulating properties have been observed. In the pathogenesis of depression disturbance in neurotransmitters, increased inflammatory processes, defects in neurogenesis and synaptic plasticity, mitochondrial dysfunction, and redox imbalance are observed. Ginkgo biloba, green tea, and Quercus robur extracts and curcumin can affect neuronal system in depressive patients. ADHD patients treated with antipsychotic drugs, especially stimulants, report significant adverse effects; therefore, an alternative treatment is searched for. An extract from Ginkgo biloba and from Pinus pinaster bark, Pycnogenol, could become promising complementary supplements in ADHD treatment. Schizophrenia is a devastating mental disorder, with oxidative stress involved in its pathophysiology. The direct interference of polyphenols with schizophrenia pathophysiology has not been reported yet. However, increased oxidative stress caused by haloperidol was inhibited ex vivo by different polyphenols. Curcumin, extract from green tea and from Ginkgo biloba, may have benefits on serious side effects associated with administration of neuroleptics to patients suffering from schizophrenia. Polyphenols in the diet have the potential to become medicaments in the field of mental health after a thorough study of their mechanism of action.]]></description>
<dc:subject>polyphenols depression psychotropics treatment peer-reviewed research overview .Plexus pycogenol green tea extract gingko .week2</dc:subject>
<dc:source>https://pinboard.in/</dc:source>
<dc:identifier>https://pinboard.in/u:Michael.Massing/b:48c275b48dd9/</dc:identifier>
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	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:gingko"/>
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</item>
<item rdf:about="https://www.ncbi.nlm.nih.gov/pubmed/23642183">
    <title>Natural polyphenols in the management of major depression. - PubMed - NCBI</title>
    <dc:date>2017-03-13T17:11:17+00:00</dc:date>
    <link>https://www.ncbi.nlm.nih.gov/pubmed/23642183</link>
    <dc:creator>Michael.Massing</dc:creator><description><![CDATA[Natural polyphenols, the non-essential micronutrients, found in array of plant products, are known to affect various physiological and biochemical functions in the body. Studies have shown the protective effect of these polyphenols in different neurological and mental disorders. These polyphenols modulate monoaminergic neurotransmission in the brain and thus possess antidepressant-like activity at least in animal models of depression.
AREAS COVERED:
The present review discusses the use of these natural polyphenols in the treatment of major depression. The review article discusses the antidepressant potential of some important polyphenols such as amentoflavone, apigenin, chlorogenic acid, curcumin, ferulic acid, hesperidin, rutin, quercetin, naringenin, resveratrol, ellagic acid, nobiletin and proanthocyanidins. The mechanism of action of these polyphenols in the treatment of major depression is also discussed in detail.
EXPERT OPINION:
There is an exciting prospect in the discovery of natural polyphenols as therapeutic agents in the treatment of major depression.]]></description>
<dc:subject>polyphenols depression psychotropics treatment peer-reviewed research chlorogenic acid .Plexus .week2</dc:subject>
<dc:source>https://pinboard.in/</dc:source>
<dc:identifier>https://pinboard.in/u:Michael.Massing/b:a58b498575c1/</dc:identifier>
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</item>
<item rdf:about="http://care.diabetesjournals.org/content/40/Supplement_1/S4.full">
    <title>Diabetes Care</title>
    <dc:date>2016-12-26T03:44:02+00:00</dc:date>
    <link>http://care.diabetesjournals.org/content/40/Supplement_1/S4.full</link>
    <dc:creator>Michael.Massing</dc:creator><dc:subject>ADA American Diabetes Association psychosocial symptoms stress depression anxiety eating disorders erectile dysfunction ED standards of care cognition</dc:subject>
<dc:source>https://pinboard.in/</dc:source>
<dc:identifier>https://pinboard.in/u:Michael.Massing/b:905415e9e4d2/</dc:identifier>
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</item>
<item rdf:about="http://clinical.diabetesjournals.org/content/34/1/3">
    <title>Clinical Diabetes</title>
    <dc:date>2016-12-26T03:40:46+00:00</dc:date>
    <link>http://clinical.diabetesjournals.org/content/34/1/3</link>
    <dc:creator>Michael.Massing</dc:creator><description><![CDATA[Psychosocial]]></description>
<dc:subject>ADA American Diabetes Association psychosocial symptoms stress depression anxiety eating disorders erectile dysfunction ED standards of care cognition</dc:subject>
<dc:source>https://pinboard.in/</dc:source>
<dc:identifier>https://pinboard.in/u:Michael.Massing/b:10f5e625f045/</dc:identifier>
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</item>
<item rdf:about="http://www.tudiabetes.org/forum/t/adas-new-set-of-standards-of-care-psychosocial/57541">
    <title>ADA's New Set of Standards of Care - Psychosocial - Mental and Emotional Wellness - TuDiabetes Forum</title>
    <dc:date>2016-12-26T03:34:39+00:00</dc:date>
    <link>http://www.tudiabetes.org/forum/t/adas-new-set-of-standards-of-care-psychosocial/57541</link>
    <dc:creator>Michael.Massing</dc:creator><dc:subject>ADA American Diabetes Association psychosocial symptoms stress depression anxiety eating disorders erectile dysfunction ED standard of care</dc:subject>
<dc:source>https://pinboard.in/</dc:source>
<dc:identifier>https://pinboard.in/u:Michael.Massing/b:2556fa9a0d25/</dc:identifier>
<taxo:topics><rdf:Bag>	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:ADA"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:American"/>
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</item>
<item rdf:about="https://twitter.com/i/web/status/802617957046226944">
    <title>Twitter</title>
    <dc:date>2016-11-26T21:00:07+00:00</dc:date>
    <link>https://twitter.com/i/web/status/802617957046226944</link>
    <dc:creator>Michael.Massing</dc:creator><description><![CDATA[1st set of #ADA standards for treatment of PWD that include psychosocial aspects:  stress, depression, anxiety & ED… ]]></description>
<dc:subject>ADA American Diabetes Association psychosocial symptoms stress depression anxiety eating disorders erectile dysfunction ED</dc:subject>
<dc:source>https://twitter.com/</dc:source>
<dc:identifier>https://pinboard.in/u:Michael.Massing/b:3053389df140/</dc:identifier>
<taxo:topics><rdf:Bag>	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:ADA"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:American"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:Diabetes"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:Association"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:psychosocial"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:symptoms"/>
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	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:ED"/>
</rdf:Bag></taxo:topics>
</item>
<item rdf:about="http://diabetes2remission.blogspot.com/2016/08/the-look-of-depression.html">
    <title>Diabetes 2 Remission: The poker face of depression</title>
    <dc:date>2016-08-14T23:26:28+00:00</dc:date>
    <link>http://diabetes2remission.blogspot.com/2016/08/the-look-of-depression.html</link>
    <dc:creator>Michael.Massing</dc:creator><description><![CDATA[Prelude to a forthcoming piece on #depression, along with a little housekeeping at the old blog: ]]></description>
<dc:subject>depression</dc:subject>
<dc:source>https://twitter.com/</dc:source>
<dc:identifier>https://pinboard.in/u:Michael.Massing/b:3974521b9092/</dc:identifier>
<taxo:topics><rdf:Bag>	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:depression"/>
</rdf:Bag></taxo:topics>
</item>
<item rdf:about="http://depressionarmy.tumblr.com/post/134739411999/what-depression-is-actually-like">
    <title>What depression is actually like. - Depression Army™</title>
    <dc:date>2016-07-09T16:54:43+00:00</dc:date>
    <link>http://depressionarmy.tumblr.com/post/134739411999/what-depression-is-actually-like</link>
    <dc:creator>Michael.Massing</dc:creator><dc:subject>depression feels like looks what image perception earnest</dc:subject>
<dc:source>https://pinboard.in/</dc:source>
<dc:identifier>https://pinboard.in/u:Michael.Massing/b:bc1aa6fcdbdb/</dc:identifier>
<taxo:topics><rdf:Bag>	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:depression"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:feels"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:like"/>
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	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:what"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:image"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:perception"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:earnest"/>
</rdf:Bag></taxo:topics>
</item>
<item rdf:about="https://en.wikiquote.org/wiki/Will_Rogers">
    <title>Will Rogers - Wikiquote</title>
    <dc:date>2016-04-04T16:29:08+00:00</dc:date>
    <link>https://en.wikiquote.org/wiki/Will_Rogers</link>
    <dc:creator>Michael.Massing</dc:creator><description><![CDATA[ The money was all appropriated for the top in the hopes that it would trickle down to the needy. Mr. Hoover was an engineer. He knew that water trickled down. Put it uphill and let it go and it will reach the dryest little spot. But he dident know that money trickled up. Give it to the people at the bottom and the people at the top will have it before night anyhow. But it will at least have passed through the poor fellow’s hands. They saved the big banks but the little ones went up the flue.]]></description>
<dc:subject>Will Rogers quotations wealth trickle down Herbert Hoover Great Depression US history economics</dc:subject>
<dc:source>https://pinboard.in/</dc:source>
<dc:identifier>https://pinboard.in/u:Michael.Massing/b:f1e473e235cf/</dc:identifier>
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</item>
<item rdf:about="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633390/">
    <title>The Frequency of Depression and the Comorbidity of Psychotic Disorders at Day Hospital of Psychiatric Clinic, Clinical Center of Sarajevo University</title>
    <dc:date>2016-04-02T23:04:21+00:00</dc:date>
    <link>http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633390/</link>
    <dc:creator>Michael.Massing</dc:creator><dc:subject>depression anxiety comorbidities peer-reviewed research</dc:subject>
<dc:source>https://pinboard.in/</dc:source>
<dc:identifier>https://pinboard.in/u:Michael.Massing/b:ae9571109732/</dc:identifier>
<taxo:topics><rdf:Bag>	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:depression"/>
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</item>
<item rdf:about="https://www.mja.com.au/open/2012/1/4/depression-and-anxiety">
    <title>Depression and anxiety | Medical Journal of Australia</title>
    <dc:date>2016-04-02T22:47:01+00:00</dc:date>
    <link>https://www.mja.com.au/open/2012/1/4/depression-and-anxiety</link>
    <dc:creator>Michael.Massing</dc:creator><dc:subject>depression anxiety comorbidities primary care</dc:subject>
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<item rdf:about="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC181193/">
    <title>The Comorbidity of Major Depression and Anxiety Disorders: Recognition and Management in Primary Care</title>
    <dc:date>2016-04-02T22:46:22+00:00</dc:date>
    <link>http://www.ncbi.nlm.nih.gov/pmc/articles/PMC181193/</link>
    <dc:creator>Michael.Massing</dc:creator><dc:subject>depression anxiety comorbidities primary care</dc:subject>
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<item rdf:about="http://www.adaa.org/sites/default/files/GAD_depression_symptoms%20overlap.pdf">
    <title>[untitled]</title>
    <dc:date>2016-03-28T15:58:13+00:00</dc:date>
    <link>http://www.adaa.org/sites/default/files/GAD_depression_symptoms%20overlap.pdf</link>
    <dc:creator>Michael.Massing</dc:creator><dc:subject>anxiety depression comorbidities symptoms</dc:subject>
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    <title>Comorbid depression and anxiety spectrum disorders - Gorman - 1998 - Depression and Anxiety - Wiley Online Library</title>
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    <link>http://onlinelibrary.wiley.com/doi/10.1002/(SICI)1520-6394(1996)4:4%3C160::AID-DA2%3E3.0.CO;2-J/abstract;jsessionid=8AF263CD6D49976630D4ACFD89898000.f04t01</link>
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    <title>Gorman JM. Comorbid depression and anxiety spectrum disorders. Depress Anxiety 1996-1997; 4: 160-168 - Google Search</title>
    <dc:date>2016-03-28T03:57:17+00:00</dc:date>
    <link>https://www.google.com/#newwindow=1&amp;q=Gorman+JM.+Comorbid+depression+and+anxiety+spectrum+disorders.+Depress+Anxiety+1996-1997%3B+4:+160-168</link>
    <dc:creator>Michael.Massing</dc:creator><description><![CDATA[Gorman JM. Comorbid depression and anxiety spectrum disorders. Depress Anxiety 1996-1997; 4: 160-168

[source and citations]]]></description>
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<item rdf:about="http://care.diabetesjournals.org/content/36/10/3337.abstract">
    <title>Antidepressant Medication as a Risk Factor for Type 2 Diabetes and Impaired Glucose Regulation</title>
    <dc:date>2016-03-28T02:13:46+00:00</dc:date>
    <link>http://care.diabetesjournals.org/content/36/10/3337.abstract</link>
    <dc:creator>Michael.Massing</dc:creator><description><![CDATA[Antidepressant Medication as a Risk Factor for Type 2 Diabetes and Impaired Glucose Regulation
Systematic review
Katharine Barnard, PHD1⇑, Robert C. Peveler, FRCPSYCH2 and Richard I.G. Holt, FRCP1]]></description>
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<item rdf:about="http://www.reuters.com/article/us-antidepressants-idUSBRE9970RK20131008">
    <title>More research needed on antidepressants, diabetes link | Reuters</title>
    <dc:date>2016-03-28T02:12:31+00:00</dc:date>
    <link>http://www.reuters.com/article/us-antidepressants-idUSBRE9970RK20131008</link>
    <dc:creator>Michael.Massing</dc:creator><dc:subject>diabetes depression risk comorbidities affective mood disorders correlation stress distress factor peer-reviewed research clinical in vivo situ human antidepressant SSRI systematic review etiology cause</dc:subject>
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<item rdf:about="http://www.diabetesincontrol.com/antidepressant-may-affect-glucose-metabolism/">
    <title>Antidepressant May Affect Glucose Metabolism</title>
    <dc:date>2016-03-28T01:54:01+00:00</dc:date>
    <link>http://www.diabetesincontrol.com/antidepressant-may-affect-glucose-metabolism/</link>
    <dc:creator>Michael.Massing</dc:creator><dc:subject>diabetes depression risk comorbidities affective mood disorders correlation stress distress factor peer-reviewed research clinical in vivo situ human antidepressant duloxetine SNRI glucose metabolism etiology cause</dc:subject>
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<item rdf:about="http://www.nytimes.com/health/guides/disease/major-depression/risk-factors.html">
    <title>Major Depression Risk Factors - Major Depression Health Information - NY Times Health</title>
    <dc:date>2016-03-28T00:23:08+00:00</dc:date>
    <link>http://www.nytimes.com/health/guides/disease/major-depression/risk-factors.html</link>
    <dc:creator>Michael.Massing</dc:creator><dc:subject>risk factors depression</dc:subject>
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<item rdf:about="http://www.mayoclinic.org/diseases-conditions/depression/basics/risk-factors/con-20032977">
    <title>Depression (major depression) Risk factors - Mayo Clinic</title>
    <dc:date>2016-03-28T00:15:58+00:00</dc:date>
    <link>http://www.mayoclinic.org/diseases-conditions/depression/basics/risk-factors/con-20032977</link>
    <dc:creator>Michael.Massing</dc:creator><dc:subject>depression risk factors</dc:subject>
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<item rdf:about="http://www.diabetesincontrol.com/depression-diabetes-linked-in-women/">
    <title>Depression, Diabetes Linked in Women</title>
    <dc:date>2016-03-28T00:02:38+00:00</dc:date>
    <link>http://www.diabetesincontrol.com/depression-diabetes-linked-in-women/</link>
    <dc:creator>Michael.Massing</dc:creator><description><![CDATA[For depression and incident diabetes, they found:

There were 2,844 new cases of diabetes over the 10 years of follow-up.
Compared with the reference group, participants with Mental Health Index scores of 76 through 85, 53 through 75, or 52 and below had a monotonic elevated risk of developing diabetes, and the trend was significant at P=0.002 in the multivariate analysis.
Participants with scores of 52 or less had an adjusted relative risk of developing diabetes of 1.17, with a 95% confidence interval from 1.05 to 1.30.
Those using antidepressants were at higher relative risk after adjustment for covariates — of 1.25, with a 95% confidence interval from 1.10 to 1.41.
On the other hand, the parallel analysis showed:

There were 7,415 new cases of clinical depression over the decade of follow-up.
Compared with the reference group, those with diabetes had a relative risk of developing clinical depression — after controlling for covariates – of 1.29, with a 95% confidence interval from 1.18 to 1.40.
The relative risks rose with disease severity: 1.25 and 1.24 for those without medications or using oral hypoglycemic agents, respectively, and 1.53 for those on insulin. The associations remained significant after adjusting for diabetes-related comorbidities.
Hu and colleagues noted that the study’s strengths include its large size and prospective design. On the other hand, much of the data was self-reported and the participants were registered nurses and most were white, so the results might not apply to different populations.

Practice Pearl:

Point out that this study, in conjunction with prior studies, indicates the importance of screening for depression in patients with diabetes, and screening for diabetes in patients with depression.

Pan A, et al “Bidirectional association between depression and Type 2 diabetes mellitus in women” Arch Intern Med 2010; 170(21): 1884-1891.]]></description>
<dc:subject>diabetes depression risk comorbidities affective mood disorders correlation stress distress factor peer-reviewed research clinical in vivo situ human antidepressant population prospective etiology cause</dc:subject>
<dc:source>https://pinboard.in/</dc:source>
<dc:identifier>https://pinboard.in/u:Michael.Massing/b:7dec6af5e027/</dc:identifier>
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<item rdf:about="http://www.diabetesincontrol.com/a-link-between-antidepressants-and-type-2-diabetes/">
    <title>A Link Between Antidepressants and Type 2 Diabetes</title>
    <dc:date>2016-03-27T23:18:31+00:00</dc:date>
    <link>http://www.diabetesincontrol.com/a-link-between-antidepressants-and-type-2-diabetes/</link>
    <dc:creator>Michael.Massing</dc:creator><description><![CDATA[What she found was the risk of diabetes almost doubled for the patients who were using two types of therapies at the same time, tricyclic antidepressants (TCAs) and selective serotonin reuptake inhibitors (SSRIs). Brown says people are usually prescribed multiple medications "if they have severe depression or if they are having a problem finding the right therapy."

Overall, 41.9% were taking a tricyclic antidepressant only, 38.7% were taking an SSRI only, 7.7% were taking one of each, and 11.8% were taking at least three medications, at least one of which was not a tricyclic antidepressant or SSRI.
After adjusting for age, sex, number of physician visits, and use of augmentation therapy, only use of one each of a tricyclic antidepressant and an SSRI was associated with an increased risk for type 2 diabetes compared with use of a tricyclic antidepressant alone (adjusted OR 1.89, 95% CI 1.35 to 2.65, P0.001).

Brown L, et al "Type of antidepressant therapy and risk of type 2 diabetes in people with depression"Diabetes Research and Clinical Practice 2008; DOI: 10.1016/j.diabres.2007.07.009.]]></description>
<dc:subject>diabetes depression risk comorbidities affective mood disorders correlation stress distress factor peer-reviewed research clinical in vivo situ human antidepressant tricyclic SSRI population retrospective etiology cause</dc:subject>
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	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:tricyclic"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:SSRI"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:population"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:retrospective"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:etiology"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:cause"/>
</rdf:Bag></taxo:topics>
</item>
<item rdf:about="http://www.ncbi.nlm.nih.gov/pubmed/20123914">
    <title>Depressive disorder and incident diabetes mellitus: the effect of characteristics of depression. - PubMed - NCBI</title>
    <dc:date>2016-03-27T22:34:13+00:00</dc:date>
    <link>http://www.ncbi.nlm.nih.gov/pubmed/20123914</link>
    <dc:creator>Michael.Massing</dc:creator><description><![CDATA[At baseline, 379 case subjects with depression were identified. The risk of incident diabetes mellitus was higher among subjects with depression when compared with nondepressed subjects, and the association remained significant after controlling for potential confounders, including diabetes risk factors. The estimated rate of diabetes mellitus attributable to depression was 6.87%. An increased risk of diabetes mellitus was also associated with the following characteristics of depression: nonsevere depression, persistent depression, and untreated depression. Treatment with antidepressants was not associated with an increased risk of diabetes mellitus.
CONCLUSIONS:
Clinically significant depression is associated with a 65% increased risk of diabetes mellitus. Characteristics of depression frequently found in the community, namely nonsevere depression, persistent depression, and untreated depression, may play a role in the development of diabetes in a predominantly elderly adult population.]]></description>
<dc:subject>diabetes depression risk comorbidities affective mood disorders correlation stress distress factor peer-reviewed research clinical in vivo situ human etiology public health cause</dc:subject>
<dc:source>https://pinboard.in/</dc:source>
<dc:identifier>https://pinboard.in/u:Michael.Massing/b:3154d6dc0112/</dc:identifier>
<taxo:topics><rdf:Bag>	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:diabetes"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:depression"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:risk"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:comorbidities"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:affective"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:mood"/>
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	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:cause"/>
</rdf:Bag></taxo:topics>
</item>
<item rdf:about="http://www.diabetesincontrol.com/more-info-on-depression-linked-to-increased-risk-of-diabetes/">
    <title>More Info on Depression Linked to Increased Risk of Diabetes</title>
    <dc:date>2016-03-27T22:27:36+00:00</dc:date>
    <link>http://www.diabetesincontrol.com/more-info-on-depression-linked-to-increased-risk-of-diabetes/</link>
    <dc:creator>Michael.Massing</dc:creator><description><![CDATA[A random sample of 4,803 adults from the Zaragoza Dementia and Depression Project were identified and interviewed at baseline. After excluding patients with dementia and those with diabetes at baseline, a total of 3,521 participants older than 55 years were included in this study. Of these, 379 were diagnosed as having depression (80.5% female; mean age, 73.6 years), and 3,142 were found to be nondepressed (51.9% female; mean age, 71.8 years).

Diabetes was assessed using a risk factors questionnaire, and follow-up evaluations 2.5 and 5 years later were completed to determine the incidence of diabetes.

Results showed that “the risk of incident diabetes mellitus was higher among those with depression when compared with nondepressed subjects, and the association remained significant after controlling for potential confounders, including diabetes risk factors (P = 0.04).”

The incidence rate was 19.70 per 1000 person-years for the depressed patients compared with 12.36 per 1000 person-years for the nondepressed patients.

Although the community characteristics of nonsevere, persistent, and untreated depression were associated with a significantly increased risk of diabetes compared with nondepression, treatment with antidepressants was not.

Am J Psychiatry. Published online February 1, 2010. [print edition May 2010]]]></description>
<dc:subject>diabetes depression risk comorbidities affective mood disorders correlation stress distress factor peer-reviewed research clinical in vivo situ human etiology public health cause</dc:subject>
<dc:source>https://pinboard.in/</dc:source>
<dc:identifier>https://pinboard.in/u:Michael.Massing/b:e69049ac2652/</dc:identifier>
<taxo:topics><rdf:Bag>	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:diabetes"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:depression"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:risk"/>
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</item>
<item rdf:about="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883520/">
    <title>The Effects of Depression on Metabolic Control and Quality of Life in Indigent Patients with Type 2 Diabetes</title>
    <dc:date>2016-03-27T20:44:26+00:00</dc:date>
    <link>http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883520/</link>
    <dc:creator>Michael.Massing</dc:creator><description><![CDATA[In the study sample (n = 201), approximately 20% (n = 40) were depressed. In unadjusted analyses, subjects with depression had significantly lower SF-12 physical component summary (PCS) scores (30.4 ± 7.3 vs. 39.6 ± 11.8, P < 0.001) and mental component summary (MCS) scores (32.8 ± 10.5 vs. 48.9 ± 9.2, P ≤ 0.001) and significantly higher total cholesterol (209.3 ± 72.1 vs. 186.6 ± 50.9, P = 0.024) compared to those without depression. No significant differences were observed by depression status in hemoglobin A1C, LDL cholesterol, and HDL cholesterol. After adjustment for relevant covariates, depressed individuals continued to have lower SF-12 PCS (36.1 vs. 39.0, P ≤ 0.001) and MCS (41.6 vs. 46.8, P ≤ 0.001) scores, but the difference in total cholesterol levels was no longer significant.

Conclusions

In an indigent sample with type 2 diabetes, depression is significantly associated with decreased physical and mental components of QOL. This finding further reinforces the importance of addressing depression in all populations with type 2 diabetes.]]></description>
<dc:subject>diabetes depression risk comorbidities affective mood disorders correlation stress distress factor peer-reviewed research etiology public health cause</dc:subject>
<dc:source>https://pinboard.in/</dc:source>
<dc:identifier>https://pinboard.in/u:Michael.Massing/b:506780032000/</dc:identifier>
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	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:depression"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:risk"/>
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</rdf:Bag></taxo:topics>
</item>
<item rdf:about="https://www.sciencedaily.com/releases/2012/01/120110093559.htm">
    <title>Treatment for diabetes and depression improves both, researchers say -- ScienceDaily</title>
    <dc:date>2016-03-27T18:57:44+00:00</dc:date>
    <link>https://www.sciencedaily.com/releases/2012/01/120110093559.htm</link>
    <dc:creator>Michael.Massing</dc:creator><description><![CDATA[Of patients receiving integrated care combined with a brief period of intervention to assist with adherence to prescribed medication regimens, more than 60 percent had improved blood sugar test results and 58 percent had reduced depression symptoms, compared to only 36 percent and 31 percent, respectively, of patients receiving usual care.

The full results of the study are published in the January/February issue of The Annals of Family Medicine.

There is a link between depression and diabetes - as depression is a risk factor for diabetes, diabetes also increases the risk for the onset of depression....

After 12 weeks of monitoring for medication adherence, 60.9 percent of patients who received the integrated approach were found to achieve improved blood sugar test results, compared to only 35.7 percent patients who received only the usual primary care. Additionally, patients in the integrated care group were also more likely to show signs of remission of depression in comparison with patients in the usual care group (58.7 percent vs. 30.7 percent, respectively)....

H. R. Bogner, K. H. Morales, H. F. de Vries, A. R. Cappola. Integrated Management of Type 2 Diabetes Mellitus and Depression Treatment to Improve Medication Adherence: A Randomized Controlled Trial. The Annals of Family Medicine, 2012; 10 (1): 15 DOI: 10.1370/afm.1344
]]></description>
<dc:subject>diabetes depression comorbidities treatment self care adherence integrated etiology demographics epidemiology risk glucose efficacy youth peer-reviewed research T2D medical correlation support factor stress distress drug public health cause</dc:subject>
<dc:source>https://pinboard.in/</dc:source>
<dc:identifier>https://pinboard.in/u:Michael.Massing/b:152bb9ac350b/</dc:identifier>
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	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:comorbidities"/>
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	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:care"/>
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</rdf:Bag></taxo:topics>
</item>
<item rdf:about="https://www.washingtonpost.com/news/comic-riffs/wp/2016/03/26/video-of-the-week-heres-why-sad-affleck-is-just-perfect/">
    <title>Video of the week: Here’s why ‘Sad Affleck’ is just perfect - The Washington Post</title>
    <dc:date>2016-03-27T15:16:27+00:00</dc:date>
    <link>https://www.washingtonpost.com/news/comic-riffs/wp/2016/03/26/video-of-the-week-heres-why-sad-affleck-is-just-perfect/</link>
    <dc:creator>Michael.Massing</dc:creator><description><![CDATA[This original video is ripe for parody, and the best of the bunch is the one that makes inspired use of Simon and Garfunkel. Affleck — who of course once bombed as the big-screen Daredevil — looks vulnerable concerning his new superhero turn as the Dark Knight, and the mind behind those hurt eyes seems to wander as the parody clip cues: “Hello darkness, my old friend… .”

And the effect is, well, perfection.]]></description>
<dc:subject>Variety Affleck depression Ben affect comorbidities comedy humor criticism</dc:subject>
<dc:source>https://pinboard.in/</dc:source>
<dc:identifier>https://pinboard.in/u:Michael.Massing/b:99cc82bb3569/</dc:identifier>
<taxo:topics><rdf:Bag>	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:Variety"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:Affleck"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:depression"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:Ben"/>
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	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:comorbidities"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:comedy"/>
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	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:criticism"/>
</rdf:Bag></taxo:topics>
</item>
<item rdf:about="http://variety.com/2016/film/news/sad-affleck-batman-superman-dawn-justice-1201739535/">
    <title>‘Sad Affleck’: ‘Batman v Superman’ Reviews Spawn Viral Video | Variety</title>
    <dc:date>2016-03-27T15:14:01+00:00</dc:date>
    <link>http://variety.com/2016/film/news/sad-affleck-batman-superman-dawn-justice-1201739535/</link>
    <dc:creator>Michael.Massing</dc:creator><description><![CDATA[The Man of Steel might be able to hold his composure in the face of adversity, but the Bat of Gotham? Not so much.

Fans created a video of a distraught Ben Affleck, who plays Batman in “Batman v Superman: Dawn of Justice,” after the actor appeared saddened when asked about the film’s unsettling reviews in an interview with Yahoo Movies.

Affleck’s co-star Henry Cavill, who plays Superman, kept the energy high defending “Dawn of Justice” against criticism. During Cavill’s response, Affleck cast his gaze downward and only offered a two-word answer once Cavill finished.

“I agree,” said Affleck, leaning on Cavill’s defense.

YouTube creator Sabconth edited the video interview so Affleck’s sullen expression is accompanied by Simon & Garfunkel’s “Sound of Silence.”]]></description>
<dc:subject>Variety Affleck depression Ben affect comorbidities criticism</dc:subject>
<dc:source>https://pinboard.in/</dc:source>
<dc:identifier>https://pinboard.in/u:Michael.Massing/b:6e9c96570dfe/</dc:identifier>
<taxo:topics><rdf:Bag>	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:Variety"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:Affleck"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:depression"/>
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	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:criticism"/>
</rdf:Bag></taxo:topics>
</item>
<item rdf:about="http://iamdiabetic.com/2015/10/04/natural-happiness-enhancer/">
    <title>Natural Happiness Enhancers | I Am Diabetic</title>
    <dc:date>2015-12-13T03:06:26+00:00</dc:date>
    <link>http://iamdiabetic.com/2015/10/04/natural-happiness-enhancer/</link>
    <dc:creator>Michael.Massing</dc:creator><description><![CDATA[YOGHURT

It’s rich in calcium, a mineral which can ease mood swings, depression and anxiety.

TOFU

It’s rich in protein, which increases energy levels and improves concentration. It also contains an amino acid called tyrosine, which boosts the brain chemicals norepinephrine and dopamine as well as thyroid hormone, which can all help elevate mood.]]></description>
<dc:subject>food mood tofu yogurt serotonin dopamine calcium depression anxiety self care norepinephrine</dc:subject>
<dc:source>https://pinboard.in/</dc:source>
<dc:identifier>https://pinboard.in/u:Michael.Massing/b:6218affc942a/</dc:identifier>
<taxo:topics><rdf:Bag>	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:food"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:mood"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:tofu"/>
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	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:norepinephrine"/>
</rdf:Bag></taxo:topics>
</item>
<item rdf:about="http://www.sciencedaily.com/releases/2010/06/100608182645.htm">
    <title>Molecular link between diabetes and schizophrenia connects food and mood -- ScienceDaily</title>
    <dc:date>2015-10-20T15:17:27+00:00</dc:date>
    <link>http://www.sciencedaily.com/releases/2010/06/100608182645.htm</link>
    <dc:creator>Michael.Massing</dc:creator><description><![CDATA[Galli's group was among the first to show that insulin -- the hormone that governs glucose metabolism in the body -- also regulates the brain's supply of dopamine -- a neurotransmitter with roles in motor activity, attention and reward. Disrupted dopamine signaling has been implicated in brain disorders including depression, Parkinson's disease, schizophrenia and attention-deficit hyperactivity disorder.

Now, Galli, Niswender, and colleagues have pieced together the molecular pathway between perturbed insulin signaling in the brain and dopamine dysfunction leading to schizophrenia-like behaviors....

They also showed how defects in insulin signaling disrupt neurotransmitter levels in the brain -- the mice have reduced dopamine and elevated norepinephrine in the prefrontal cortex, an important area for cognitive processes. These changes resulted from elevated levels of the transporter protein (NET) that removes norepinephrine and dopamine from the synaptic space between neurons.

"We believe the excess NET is sucking away all of the dopamine and converting it to norepinephrine, creating this situation of hypodopaminergia (low levels of dopamine) in the cortex," Galli explained. Low dopamine function in the cortex is thought to contribute to the cognitive deficits and negative symptoms -- depression, social withdrawal -- associated with schizophrenia.]]></description>
<dc:subject>diabetes correlation schizophrenia insulin neurotransmitter endocrine molecular diseaseome link genetics etiology neuroendocrine cause causation in vivo animal peer-reviewed research dopamine regulation psychotropic attention reward norepinephrine depression cognition food foods risk factor genetic</dc:subject>
<dc:source>https://pinboard.in/</dc:source>
<dc:identifier>https://pinboard.in/u:Michael.Massing/b:9bc39a261f93/</dc:identifier>
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	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:molecular"/>
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	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:norepinephrine"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:depression"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:cognition"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:food"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:foods"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:risk"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:factor"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:genetic"/>
</rdf:Bag></taxo:topics>
</item>
<item rdf:about="http://www.diabeticconnect.com/diabetes-information-articles/coping/2016-when-the-going-gets-tough-how-to-help-yourself-how-to-help-others">
    <title>When the Going Gets Tough … How to Help Yourself, How to Help Others</title>
    <dc:date>2015-07-31T18:44:11+00:00</dc:date>
    <link>http://www.diabeticconnect.com/diabetes-information-articles/coping/2016-when-the-going-gets-tough-how-to-help-yourself-how-to-help-others</link>
    <dc:creator>Michael.Massing</dc:creator><dc:subject>depression .AH comorbidities diabetes correlation stress distress risk factor etiology cause</dc:subject>
<dc:source>https://pinboard.in/</dc:source>
<dc:identifier>https://pinboard.in/u:Michael.Massing/b:c2df5cc7ebf9/</dc:identifier>
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	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:.AH"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:comorbidities"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:diabetes"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:correlation"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:stress"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:distress"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:risk"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:factor"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:etiology"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:cause"/>
</rdf:Bag></taxo:topics>
</item>
<item rdf:about="http://consumer.healthday.com/senior-citizen-information-31/misc-aging-news-10/depression-plus-diabetes-may-boost-dementia-risk-698422.html">
    <title>Depression Plus Diabetes May Boost Dementia Risk</title>
    <dc:date>2015-04-18T16:57:07+00:00</dc:date>
    <link>http://consumer.healthday.com/senior-citizen-information-31/misc-aging-news-10/depression-plus-diabetes-may-boost-dementia-risk-698422.html</link>
    <dc:creator>Michael.Massing</dc:creator><description><![CDATA[MT @healthscopeasia: Diabetes raises risk of dementia by 15%, #depression by 83% and the two together by 107%. ]]></description>
<dc:subject>depression</dc:subject>
<dc:source>https://twitter.com/</dc:source>
<dc:identifier>https://pinboard.in/u:Michael.Massing/b:da663fc82501/</dc:identifier>
<taxo:topics><rdf:Bag>	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:depression"/>
</rdf:Bag></taxo:topics>
</item>
<item rdf:about="http://www.ncbi.nlm.nih.gov/pubmed/23832433/">
    <title>Efficacy and safety of curcumin in major depressive disorder: a randomized controlled trial. - PubMed - NCBI</title>
    <dc:date>2015-04-04T23:26:50+00:00</dc:date>
    <link>http://www.ncbi.nlm.nih.gov/pubmed/23832433/</link>
    <dc:creator>Michael.Massing</dc:creator><description><![CDATA[Curcumin, an active ingredient of Curcuma longa Linn (Zingiberaceae), has shown potential antidepressant-like activity in animal studies. The objectives of this trial were to compare the efficacy and safety of curcumin with fluoxetine in patients with major depressive disorder (MDD). Herein, 60 patients diagnosed with MDD were randomized in a 1:1:1 ratio for six weeks observer-masked treatment with fluoxetine (20 mg) and curcumin (1000 mg) individually or their combination. The primary efficacy variable was response rates according to Hamilton Depression Rating Scale, 17-item version (HAM-D17 ). The secondary efficacy variable was the mean change in HAM-D17 score after six weeks. We observed that curcumin was well tolerated by all the patients. The proportion of responders as measured by the HAM-D17 scale was higher in the combination group (77.8%) than in the fluoxetine (64.7%) and the curcumin (62.5%) groups; however, these data were not statistically significant (P = 0.58). Interestingly, the mean change in HAM-D17 score at the end of six weeks was comparable in all three groups (P = 0.77). This study provides first clinical evidence that curcumin may be used as an effective and safe modality for treatment in patients with MDD without concurrent suicidal ideation or other psychotic disorders. 

Phytother Res. 2014 Apr;28(4):579-85. doi: 10.1002/ptr.5025. Epub 2013 Jul 6.
Efficacy and safety of curcumin in major depressive disorder: a randomized controlled trial.
Sanmukhani J1, Satodia V, Trivedi J, Patel T, Tiwari D, Panchal B, Goel A, Tripathi CB.]]></description>
<dc:subject>curcumin supplements depression psychotropic treatment peer-reviewed research in vivo human antidepressant comparison fluoxetine clinical trial</dc:subject>
<dc:source>https://pinboard.in/</dc:source>
<dc:identifier>https://pinboard.in/u:Michael.Massing/b:a388e21fc1c2/</dc:identifier>
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	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:fluoxetine"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:clinical"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:trial"/>
</rdf:Bag></taxo:topics>
</item>
<item rdf:about="http://www.nytimes.com/2015/03/01/opinion/sunday/medicating-womens-feelings.html?_r=3">
    <title>Medicating Women’s Feelings - NYTimes.com</title>
    <dc:date>2015-03-08T02:10:00+00:00</dc:date>
    <link>http://www.nytimes.com/2015/03/01/opinion/sunday/medicating-womens-feelings.html?_r=3</link>
    <dc:creator>Michael.Massing</dc:creator><description><![CDATA[But at what cost? I had a patient who called me from her office in tears, saying she needed to increase her antidepressant dosage because she couldn’t be seen crying at work. After dissecting why she was upset — her boss had betrayed and humiliated her in front of her staff — we decided that what was needed was calm confrontation, not more medication.]]></description>
<dc:subject>women health mental power office politics complaisance medication overmedication SSRI antidepressant depression anxiety</dc:subject>
<dc:source>https://pinboard.in/</dc:source>
<dc:identifier>https://pinboard.in/u:Michael.Massing/b:07401a1cb486/</dc:identifier>
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	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:anxiety"/>
</rdf:Bag></taxo:topics>
</item>
<item rdf:about="http://op-talk.blogs.nytimes.com/2014/11/26/what-if-were-wrong-about-depression/?_r=0">
    <title>What If We’re Wrong About Depression? - NYTimes.com</title>
    <dc:date>2015-01-30T01:10:03+00:00</dc:date>
    <link>http://op-talk.blogs.nytimes.com/2014/11/26/what-if-were-wrong-about-depression/?_r=0</link>
    <dc:creator>Michael.Massing</dc:creator><description><![CDATA[His team has experimented with treating depressed patients with an anti-inflammatory drug, and found that those with high levels of a particular blood marker for inflammation improved significantly. “This for us in psychiatry is a first,” he said, “where you can actually measure something in the blood.” Such an approach “gets into personalized medicine in a way that is very exciting for us in psychiatry.”

However, he cautioned, “nobody’s figured out what’s the best anti-inflammatory.” And most researchers “are still at the point of the proof of concept, making sure that if you do in fact block inflammation that that would reduce these behavioral changes.”

Dr. Miller also noted that only about 20 to 30 percent of depressed patients show high levels of inflammation. These patients are also less likely than others to respond well to current forms of treatment for depression.

Indeed, what many researchers seem to agree on is that depression may not be one illness at all. It’s “probably the case that it’s not a single disorder,” said Dr. Hollon. “It’s probably the fever of modern psychiatry — a lot of different things can cause it.”]]></description>
<dc:subject>risk inflammation trauma childhood evolution depression adaptation etiology treatment theory factor</dc:subject>
<dc:identifier>https://pinboard.in/u:Michael.Massing/b:9cce2b6a1d1c/</dc:identifier>
<taxo:topics><rdf:Bag>	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:risk"/>
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	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:trauma"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:childhood"/>
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	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:depression"/>
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</item>
<item rdf:about="http://genealogyblog.geneanet.org/index.php/post/2014/09/A-New-Project-from-Yale-Invites-Viewers-To-Explore-Some-175000-Images-of-America-in-the-1930s-and-40s.html">
    <title>A New Project from Yale Invites Viewers To Explore Some 175,000 Images of America in the 1930s and '40s - Genealogy Blog - Geneanet</title>
    <dc:date>2014-09-25T14:39:41+00:00</dc:date>
    <link>http://genealogyblog.geneanet.org/index.php/post/2014/09/A-New-Project-from-Yale-Invites-Viewers-To-Explore-Some-175000-Images-of-America-in-the-1930s-and-40s.html</link>
    <dc:creator>Michael.Massing</dc:creator><dc:subject>genealogy Great Depression FSA photographs images Yale history US</dc:subject>
<dc:source>https://pinboard.in/</dc:source>
<dc:identifier>https://pinboard.in/u:Michael.Massing/b:0ec78008ea16/</dc:identifier>
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	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:Depression"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:FSA"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:photographs"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:images"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:Yale"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:history"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:US"/>
</rdf:Bag></taxo:topics>
</item>
<item rdf:about="http://www.sciencedaily.com/releases/2014/03/140331153525.htm">
    <title>Kinder, gentler med school: Students less depressed, learn more -- ScienceDaily</title>
    <dc:date>2014-04-06T00:35:23+00:00</dc:date>
    <link>http://www.sciencedaily.com/releases/2014/03/140331153525.htm</link>
    <dc:creator>Michael.Massing</dc:creator><description><![CDATA[Medical school students learn more and are mentally healthier when pressure in medical school is reduced and they are taught stress management skills, a new study shows. The study looks at the well-being of first and second year students before and after changes a medical school curriculum that are designed to prevent depression, stress and anxiety.]]></description>
<dc:subject>depression stress cognition learning brain medical school training education reform peer-reviewed research</dc:subject>
<dc:source>https://pinboard.in/</dc:source>
<dc:identifier>https://pinboard.in/u:Michael.Massing/b:1524d1098fba/</dc:identifier>
<taxo:topics><rdf:Bag>	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:depression"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:stress"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:cognition"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:learning"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:brain"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:medical"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:school"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:training"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:education"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:reform"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:peer-reviewed"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:research"/>
</rdf:Bag></taxo:topics>
</item>
<item rdf:about="http://www.medicalnewstoday.com/releases/270967.php">
    <title>Discovery of new mechanism underlying depression could lead to efficient and fast-acting antidepressant drugs - Medical News Today</title>
    <dc:date>2014-02-03T18:53:28+00:00</dc:date>
    <link>http://www.medicalnewstoday.com/releases/270967.php</link>
    <dc:creator>Michael.Massing</dc:creator><description><![CDATA[Discovery of new mechanism underlying depression could lead to efficient and fast-acting antidepressant drugs ]]></description>
<dc:subject>in vivo animal correlation peer-reviewed research brain depression glia microglia stress response neurogenesis intervention inflammation treatment</dc:subject>
<dc:source>https://pinboard.in/</dc:source>
<dc:identifier>https://pinboard.in/u:Michael.Massing/b:7766d2a574a9/</dc:identifier>
<taxo:topics><rdf:Bag>	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:in"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:vivo"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:animal"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:correlation"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:peer-reviewed"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:research"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:brain"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:depression"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:glia"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:microglia"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:stress"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:response"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:neurogenesis"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:intervention"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:inflammation"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:treatment"/>
</rdf:Bag></taxo:topics>
</item>
<item rdf:about="http://www.mayoclinic.org/anger-management/ART-20045434/?pubDate=01%2F22%2F2014&amp;xid=nl_MayoClinicHousecall_20140122&amp;7332038=1">
    <title>Anger management: 10 tips to tame your temper - Mayo Clinic</title>
    <dc:date>2014-01-30T19:14:40+00:00</dc:date>
    <link>http://www.mayoclinic.org/anger-management/ART-20045434/?pubDate=01%2F22%2F2014&amp;xid=nl_MayoClinicHousecall_20140122&amp;7332038=1</link>
    <dc:creator>Michael.Massing</dc:creator><description><![CDATA[@MayoClinic: Not bad tips, though perhaps #10 should be #1. Sometimes #anger IS as much feeling as #depression allows ]]></description>
<dc:subject>depression anger 10</dc:subject>
<dc:source>https://twitter.com/</dc:source>
<dc:identifier>https://pinboard.in/u:Michael.Massing/b:16d5f38898e2/</dc:identifier>
<taxo:topics><rdf:Bag>	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:depression"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:anger"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:10"/>
</rdf:Bag></taxo:topics>
</item>
<item rdf:about="http://lacrossetribune.com/news/local/for-some-deep-freeze-triggers-winter-blues/article_d58b2105-ed25-59c0-a91c-2ca2ac1caa52.html">
    <title>For some, deep freeze triggers winter blues</title>
    <dc:date>2014-01-28T21:15:18+00:00</dc:date>
    <link>http://lacrossetribune.com/news/local/for-some-deep-freeze-triggers-winter-blues/article_d58b2105-ed25-59c0-a91c-2ca2ac1caa52.html</link>
    <dc:creator>Michael.Massing</dc:creator><description><![CDATA[RT @MayoClinicHS: For some, deep freeze triggers winter blues: 
@LaCrosseTribune 
#Depression]]></description>
<dc:subject>Depression</dc:subject>
<dc:source>https://twitter.com/</dc:source>
<dc:identifier>https://pinboard.in/u:Michael.Massing/b:cc6c62084213/</dc:identifier>
<taxo:topics><rdf:Bag>	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:Depression"/>
</rdf:Bag></taxo:topics>
</item>
<item rdf:about="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384508/">
    <title>Glycemic Control Among Latinos with Type 2 Diabetes: The Role of Social-Environmental Support Resources</title>
    <dc:date>2014-01-21T00:14:46+00:00</dc:date>
    <link>http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384508/</link>
    <dc:creator>Michael.Massing</dc:creator><description><![CDATA[Participants who perceived greater support resources for disease-management reported better diabetes self-management (β = .40, p < .001) and less depression (β = −.19, p < .01). In turn, better diabetes self-management and less depression were associated with tighter glycemic control ]]></description>
<dc:subject>diabetes self care management outcomes social support blood glucose control depression</dc:subject>
<dc:source>https://pinboard.in/</dc:source>
<dc:identifier>https://pinboard.in/u:Michael.Massing/b:096e7242f8c7/</dc:identifier>
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	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:self"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:care"/>
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	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:outcomes"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:social"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:support"/>
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	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:control"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:depression"/>
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</item>
<item rdf:about="https://pinboard.in/u:Michael.Massing/t:social+support+T2D">
    <title>Pinboard: bookmarks for Michael.Massing tagged 'social+support+t2d'</title>
    <dc:date>2014-01-07T19:29:01+00:00</dc:date>
    <link>https://pinboard.in/u:Michael.Massing/t:social+support+T2D</link>
    <dc:creator>Michael.Massing</dc:creator><description><![CDATA[Social media and social support help manage type 2 #diabetes and its common #comorbidity #depression. ]]></description>
<dc:subject>depression diabetes comorbidities correlation stress distress risk factor etiology public health cause</dc:subject>
<dc:source>https://twitter.com/</dc:source>
<dc:identifier>https://pinboard.in/u:Michael.Massing/b:0428bccbcf11/</dc:identifier>
<taxo:topics><rdf:Bag>	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:depression"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:diabetes"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:comorbidities"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:correlation"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:stress"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:distress"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:risk"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:factor"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:etiology"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:public"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:health"/>
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</item>
<item rdf:about="http://pinboard.in/u:Michael.Massing/t:etiology/t:diabetes/">
    <title>Pinboard: bookmarks for Michael.Massing tagged 'etiology+diabetes'</title>
    <dc:date>2013-12-02T04:13:35+00:00</dc:date>
    <link>http://pinboard.in/u:Michael.Massing/t:etiology/t:diabetes/</link>
    <dc:creator>Michael.Massing</dc:creator><description><![CDATA[@diabetesfacts What Causes #Diabetes? #Type2, #T2D: #genetics #pollution #plastics #insecticides #depression (?) ... ]]></description>
<dc:subject>plastics Type2 depression insecticides Diabetes T2D genetics pollution genetic risk etiology cause factor factors</dc:subject>
<dc:source>https://twitter.com/</dc:source>
<dc:identifier>https://pinboard.in/u:Michael.Massing/b:085e5b05b2e6/</dc:identifier>
<taxo:topics><rdf:Bag>	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:plastics"/>
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	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:insecticides"/>
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</item>
<item rdf:about="http://EverydayHealth.com">
    <title>(503) http://EverydayHealth.com</title>
    <dc:date>2013-09-21T17:55:12+00:00</dc:date>
    <link>http://EverydayHealth.com</link>
    <dc:creator>Michael.Massing</dc:creator><description><![CDATA[RT @carlmingmoon: 8 Ways to Get Through the Day When You're Depressed - #Depression Center -  ]]></description>
<dc:subject>Depression</dc:subject>
<dc:source>https://twitter.com/</dc:source>
<dc:identifier>https://pinboard.in/u:Michael.Massing/b:b647f59be898/</dc:identifier>
<taxo:topics><rdf:Bag>	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:Depression"/>
</rdf:Bag></taxo:topics>
</item>
<item rdf:about="http://www.everydayhealth.com/depression/8-ways-to-get-through-the-day-when-depressed.aspx">
    <title>8 Ways to Get Through the Day When You're Depressed - Depression Center - EverydayHealth.com</title>
    <dc:date>2013-09-21T17:55:12+00:00</dc:date>
    <link>http://www.everydayhealth.com/depression/8-ways-to-get-through-the-day-when-depressed.aspx</link>
    <dc:creator>Michael.Massing</dc:creator><description><![CDATA[RT @carlmingmoon: 8 Ways to Get Through the Day When You're Depressed - #Depression Center -  ]]></description>
<dc:subject>Depression</dc:subject>
<dc:source>https://twitter.com/</dc:source>
<dc:identifier>https://pinboard.in/u:Michael.Massing/b:70f896989488/</dc:identifier>
<taxo:topics><rdf:Bag>	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:Depression"/>
</rdf:Bag></taxo:topics>
</item>
<item rdf:about="http://www.biomedcentral.com/1741-7015/11/3">
    <title>BMC Medicine | Full text | Diet, a new target to prevent depression?</title>
    <dc:date>2013-08-21T20:55:50+00:00</dc:date>
    <link>http://www.biomedcentral.com/1741-7015/11/3</link>
    <dc:creator>Michael.Massing</dc:creator><description><![CDATA[RT @pfanderson: Diet, a new target to prevent depression?  #psych #mhealth #mental #health #depression #nutrition #diet]]></description>
<dc:subject>depression diet mental mhealth psych nutrition health</dc:subject>
<dc:source>https://twitter.com/</dc:source>
<dc:identifier>https://pinboard.in/u:Michael.Massing/b:23be2b5ae34f/</dc:identifier>
<taxo:topics><rdf:Bag>	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:depression"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:diet"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:mental"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:mhealth"/>
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</item>
<item rdf:about="http://www.clinicalendocrinologynews.com/news/top-news/single-article/depression-linked-to-accelerated-cognitive-decline-in-diabetes/28792595a47b40964c12715b635dd995.html">
    <title>Depression linked to accelerated cognitive decline in diabetes : Clinical Endocrinology News</title>
    <dc:date>2013-08-17T04:41:03+00:00</dc:date>
    <link>http://www.clinicalendocrinologynews.com/news/top-news/single-article/depression-linked-to-accelerated-cognitive-decline-in-diabetes/28792595a47b40964c12715b635dd995.html</link>
    <dc:creator>Michael.Massing</dc:creator><description><![CDATA[RT @JoslinDiabetes: A concern for caregivers:#diabetes patients w/ #depression may have more difficulty adheringtreatment recommendations ]]></description>
<dc:subject>depression diabetes</dc:subject>
<dc:source>https://twitter.com/</dc:source>
<dc:identifier>https://pinboard.in/u:Michael.Massing/b:e9e14bef2746/</dc:identifier>
<taxo:topics><rdf:Bag>	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:depression"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:diabetes"/>
</rdf:Bag></taxo:topics>
</item>
<item rdf:about="http://diabetes2remission.blogspot.com/2012/02/what-they-don-say-enough.html">
    <title>Diabetes Remission: what they don't say (enough)</title>
    <dc:date>2013-08-12T18:18:28+00:00</dc:date>
    <link>http://diabetes2remission.blogspot.com/2012/02/what-they-don-say-enough.html</link>
    <dc:creator>Michael.Massing</dc:creator><description><![CDATA[Diabetes is complicated. Volumes of research produce inconclusive and contradictory results.
Diabetes-related research may be badly reported, or just plain bad.
Evaluating research, assessing risks and benefits, and devising a working strategy for self care are not helped by the cognitive deficits, depression, and fatigue associated with blood sugar highs and lows.
Drugs used to treat diabetes and/or its comorbidities may increase the risk of death or morbidity, including onset of diabetes itself and incidence of comorbidities. 
Blacks, Hispanics, American Indians, and Pacific Islanders are known to be at higher risk for developing diabetes. Less discussed are the risks conferred by a range of circumstances: socioeconomic status, stress, sleep, inadequate health literacy and education, location, and exposure to plastics and to environmental pollution. These factors often trump genetics; they can increase diabetes incidence and/or worsen outcomes.
Lack of professional consensus, balky insurance plans, and physicians' disregard of patient-reported data may all interfere with getting adequate testing supplies to carry out tight glucose control.]]></description>
<dc:subject>T2D diabetes type 2 etiology correlation research peer-reviewed remission factor tight control glucose benefit self-monitored blood self monitoring SMBG plastics depression comorbidities stress distress risk management treatment genetic genetics insurance cause factors</dc:subject>
<dc:source>https://pinboard.in/</dc:source>
<dc:identifier>https://pinboard.in/u:Michael.Massing/b:0523a56c0964/</dc:identifier>
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	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:management"/>
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	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:genetics"/>
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	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:factors"/>
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</item>
<item rdf:about="http://www.mayoclinic.com/health/natural-remedies-for-depression/AN02087/">
    <title>Natural remedies for depression: Are they effective? - MayoClinic.com</title>
    <dc:date>2013-08-10T03:08:42+00:00</dc:date>
    <link>http://www.mayoclinic.com/health/natural-remedies-for-depression/AN02087/</link>
    <dc:creator>Michael.Massing</dc:creator><description><![CDATA[RT @MayoClinic: 4 natural remedies for #depression that show promise. ]]></description>
<dc:subject>depression</dc:subject>
<dc:source>https://twitter.com/</dc:source>
<dc:identifier>https://pinboard.in/u:Michael.Massing/b:bad2ed84aa8f/</dc:identifier>
<taxo:topics><rdf:Bag>	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:depression"/>
</rdf:Bag></taxo:topics>
</item>
<item rdf:about="http://psychcentral.com/blog/archives/2013/07/11/7-foods-that-may-contribute-to-your-depression/">
    <title>7 Foods That May Contribute to Your Depression | World of Psychology</title>
    <dc:date>2013-07-11T23:08:35+00:00</dc:date>
    <link>http://psychcentral.com/blog/archives/2013/07/11/7-foods-that-may-contribute-to-your-depression/</link>
    <dc:creator>Michael.Massing</dc:creator><description><![CDATA[RT @carlmingmoon: 7 Foods That May Contribute to Your Depression   via @psychcentral #CMMDepression  #Depression]]></description>
<dc:subject>CMMDepression Depression</dc:subject>
<dc:source>https://twitter.com/</dc:source>
<dc:identifier>https://pinboard.in/u:Michael.Massing/b:6ed0eceb448b/</dc:identifier>
<taxo:topics><rdf:Bag>	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:CMMDepression"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:Depression"/>
</rdf:Bag></taxo:topics>
</item>
<item rdf:about="https://pinboard.in/u:Michael.Massing/t:diabetes+anxiety#">
    <title>Pinboard: bookmarks for Michael.Massing tagged 'diabetes+anxiety'</title>
    <dc:date>2013-07-06T19:01:28+00:00</dc:date>
    <link>https://pinboard.in/u:Michael.Massing/t:diabetes+anxiety#</link>
    <dc:creator>Michael.Massing</dc:creator><description><![CDATA[Talk about depression and diabetes—or depression itself—often ignores 90% comorbidity between depression and anxiety ]]></description>
<dc:subject>depression diabetes correlation comorbidities stress distress risk factor etiology cause</dc:subject>
<dc:source>https://twitter.com/</dc:source>
<dc:identifier>https://pinboard.in/u:Michael.Massing/b:af95d1f597f2/</dc:identifier>
<taxo:topics><rdf:Bag>	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:depression"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:diabetes"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:correlation"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:comorbidities"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:stress"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:distress"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:risk"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:factor"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:etiology"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:cause"/>
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</item>
<item rdf:about="http://www.time-to-change.org.uk/blog/male-depression-lets-not-be-strong-silent-types">
    <title>Male depression: let's not be strong, silent types | Time To Change</title>
    <dc:date>2013-07-05T22:07:37+00:00</dc:date>
    <link>http://www.time-to-change.org.uk/blog/male-depression-lets-not-be-strong-silent-types</link>
    <dc:creator>Michael.Massing</dc:creator><description><![CDATA[RT @carlmingmoon: Men and #depression: let's not be strong silent types ]]></description>
<dc:subject>depression</dc:subject>
<dc:source>https://twitter.com/</dc:source>
<dc:identifier>https://pinboard.in/u:Michael.Massing/b:dafc9e86059c/</dc:identifier>
<taxo:topics><rdf:Bag>	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:depression"/>
</rdf:Bag></taxo:topics>
</item>
<item rdf:about="http://www.aboutdepressionfacts.com/online-depression-test-zung-self-rating-depression-scale.html">
    <title>Online Depression Test - The Zung Depression Scale</title>
    <dc:date>2013-07-05T22:07:22+00:00</dc:date>
    <link>http://www.aboutdepressionfacts.com/online-depression-test-zung-self-rating-depression-scale.html</link>
    <dc:creator>Michael.Massing</dc:creator><description><![CDATA[RT @carlmingmoon: Online #Depression Test The #Zung Depression Scale ]]></description>
<dc:subject>Zung Depression</dc:subject>
<dc:source>https://twitter.com/</dc:source>
<dc:identifier>https://pinboard.in/u:Michael.Massing/b:e3f175444ca6/</dc:identifier>
<taxo:topics><rdf:Bag>	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:Zung"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:Depression"/>
</rdf:Bag></taxo:topics>
</item>
<item rdf:about="http://well.blogs.nytimes.com/2013/07/01/new-approach-to-depression/?smid=tw-nytimeswell">
    <title>New Approach to Depression - NYTimes.com</title>
    <dc:date>2013-07-02T02:05:01+00:00</dc:date>
    <link>http://well.blogs.nytimes.com/2013/07/01/new-approach-to-depression/?smid=tw-nytimeswell</link>
    <dc:creator>Michael.Massing</dc:creator><dc:subject>depression treatment peer-reviewed research clinical human in vivo trial</dc:subject>
<dc:identifier>https://pinboard.in/u:Michael.Massing/b:67c3d3ff809a/</dc:identifier>
<taxo:topics><rdf:Bag>	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:depression"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:treatment"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:peer-reviewed"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:research"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:clinical"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:human"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:in"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:vivo"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:trial"/>
</rdf:Bag></taxo:topics>
</item>
<item rdf:about="http://www.nejm.org/doi/full/10.1056/NEJMe1306987">
    <title>Do Lifestyle Changes Reduce Serious Outcomes in Diabetes? — NEJM</title>
    <dc:date>2013-06-29T05:35:21+00:00</dc:date>
    <link>http://www.nejm.org/doi/full/10.1056/NEJMe1306987</link>
    <dc:creator>Michael.Massing</dc:creator><description><![CDATA[The participants who received intensive lifestyle modifications experienced other benefits when compared to the diabetes education and support group, including decreased depressive symptoms, less self-reported retinopathy, and decreased risk of kidney disease.  Compared to the diabetes support and education group, the intensive lifestyle intervention reduced the average number of hospitalizations per year and the average number of medications per year. Hospitalizations were reduced by 11.9% from 0.193 to 0.17 hospitalizations per year, which translated into savings of $294 per year and $2,600 discounted over 10 years.  Moreover, the number of medications was reduced by 6.3% from 4.9 to 4.6 medications per year, translating into a savings of $278 per year and $2,487 discounted over 10 years. Average costs per year were $8,807 for the control group vs. $8,205 for the intervention group, leading to a significant reduction of $602 per year and $5,378 discounted over 10 years.  Significant reductions in hospitalizations occurred mainly among CV and pulmonary hospitalization, and significant reductions in medications occurred mainly among diabetes, lipid-lowering and antihypertensive medications.  The study ultimately shows that obese or overweight people with type 2 diabetes should increase the amount that they exercise and increase their weight loss.]]></description>
<dc:subject>peer-reviewed research cardiovascular risk diabetes obesity human in vivo physical activity type 2 T2D correlation support treatment self care education depression comorbidities intensive lifestyle intervention retinopathy kidney disease hospitalization morbidity healthcare cost economics harm reduction behavioral change management behavior tight control exercise body fat clinical trial stress distress factor therapy etiology mitigation prevention symptoms late-stage complications benefit situ cause</dc:subject>
<dc:identifier>https://pinboard.in/u:Michael.Massing/b:61128166265a/</dc:identifier>
<taxo:topics><rdf:Bag>	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:peer-reviewed"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:research"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:cardiovascular"/>
	<rdf:li rdf:resource="https://pinboard.in/u:Michael.Massing/t:risk"/>
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